The humanized mouse models market refers to the segment of the biomedical research industry that focuses on the development and utilization of mice that have been genetically modified to carry human genes, tissues, or cells. These humanized mouse models are used to study human diseases, test therapeutic interventions, and understand human physiology in a more clinically relevant context.
Humanized mouse models play a vital role in biomedical research as they allow scientists to investigate human-specific diseases and conditions that cannot be adequately studied in non-human animals or cell cultures alone. By introducing human genetic material or cells into mice, researchers can mimic human biology, disease processes, and immune responses, providing a valuable platform for studying human diseases and evaluating potential treatments.
There are different types of humanized mouse models used in research, including:
- Xenograft Models: These models involve transplanting human tumor tissues or cells into immunodeficient mice. They are commonly used to study cancer biology, tumor growth, metastasis, and drug efficacy.
- Human Immune System (HIS) Models: These models are created by engrafting human immune cells, such as T cells, B cells, and hematopoietic stem cells, into immunodeficient mice. HIS models allow researchers to study human immune responses, infectious diseases, autoimmune disorders, and evaluate immunotherapies.
- Humanized Liver Models: These models involve transplanting human liver cells into mice to study liver diseases, drug metabolism, toxicity, and evaluate potential therapies.
- Humanized Bone Marrow Models: These models are created by replacing mouse bone marrow cells with human hematopoietic stem cells. They are used to study blood disorders, immune system development, and infectious diseases.
- Humanized Mouse Models for Specific Diseases: Researchers also create humanized mouse models specific to certain diseases, such as Alzheimer’s disease, Parkinson’s disease, HIV/AIDS, and diabetes, among others. These models allow for the investigation of disease mechanisms, testing potential therapies, and understanding disease progression.
The humanized mouse models market is driven by the increasing demand for better preclinical models that closely recapitulate human physiology, the growing emphasis on personalized medicine and precision therapeutics, and the need to reduce reliance on traditional animal models.
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Market Segmentations:
Global Humanized Mouse Models Market: By Company
• The Jackson Laboratory
• Taconic Biosciences
• Crown Bioscience
• Champions Oncology
• Horizon Discovery
• Hera Biolabs
• Genoway
• Vitalstar Biotechnology
• Ingenious Targeting Laboratory
• Axenis
• Trans Genic
• Harbour Antibodies
• Charles River Laboratories
Global Humanized Mouse Models Market: By Type
• Genetic Humanized Mouse Models
• Cell-based Humanized Mouse Models
Global Humanized Mouse Models Market: By Application
• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations
• Academic & Research Institutions
Global Humanized Mouse Models Market: Regional Analysis
All the regional segmentation has been studied based on recent and future trends, and the market is forecasted throughout the prediction period. The countries covered in the regional analysis of the Global Humanized Mouse Models market report are U.S., Canada, and Mexico in North America, Germany, France, U.K., Russia, Italy, Spain, Turkey, Netherlands, Switzerland, Belgium, and Rest of Europe in Europe, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, China, Japan, India, South Korea, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), and Argentina, Brazil, and Rest of South America as part of South America.
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